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Polymorphism of DNA ligase I and risk of lung cancer—a case-control analysis

✍ Scribed by Shen, Hongbing; Spitz, Margaret R.; Qiao, Yawei; Zheng, Yuxin; Hong, Waun K.; Wei, Qingyi

Book ID
118570788
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
112 KB
Volume
36
Category
Article
ISSN
0169-5002

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## Abstract Tobacco smoking is a major risk factor for lung and upper‐aerodigestive‐tract (UADT) cancers. One possible mechanism for the associations may be through DNA damage pathways. DNA Ligase I (__LIG1__) is a DNA repair gene involved in both the nucleotide excision repair (NER) and the base e