Polymorphism of Cystic Fibrosis Gene in Japanese Patients with Chronic Pancreatitis
โ Scribed by Sachiko Kimura; Yoshinori Okabayashi; Koichi Inushima; Yoshihiro Yutsudo; Masato Kasuga
- Book ID
- 110225318
- Publisher
- Springer US
- Year
- 2000
- Tongue
- English
- Weight
- 435 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0163-2116
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Communicated by Garry R. Cutting Cystic fibrosis (CF) is a recessive disease caused by mutations of the CF transmembrane conductance regulator (CFTR) gene. The risk of idiopathic chronic pancreatitis (ICP) is increased in individuals who have CFTR genotypes containing a CF-causing mutation plus
To determine the number and frequency of mutations that occur at the cystic fibrosis locus (CF), we have examined the allele and haplotype frequencies of eight polymorphic DNA markers linked to CF in 163 Italian patients who were sub-divided according to their clinical presentations. The distributio