Polymorphism of Active Pharmaceutical Ingredients
β Scribed by P. H. Karpinski
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 413 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0930-7516
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π SIMILAR VOLUMES
Near infrared (NIR) spectroscopy was used for quantitatively monitoring polymorph conversion of an active pharmaceutical ingredient (API) in wet granulation. The API under pharmaceutical development has two different polymorphs. Polymorph A is the stable form for drug development and polymorph B is
The amount of water vapor taken up by an active pharmaceutical ingredient (API) as a function of relative humidity is routinely evaluated to characterize and monitor its "hygroscopicity" throughout the drug development process. In this minireview we address the necessity of going beyond the measurem