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Polymorphism in the upstream regulatory regions ofHLA-DRBgenes

✍ Scribed by D. P. Singal; X. Qiu; M. D'Souza; S. K. Sood


Book ID
104668677
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
511 KB
Volume
37
Category
Article
ISSN
0093-7711

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Polymorphism in the regulatory region of
✍ Pascale Louis; Jean-FranΓ§ois Eliaou; Sophie Kerlan-Candon; ValΓ©rie Pinet; Rachel πŸ“‚ Article πŸ“… 1993 πŸ› Springer-Verlag 🌐 English βš– 596 KB

Class II genes of the human major histocompatibility complex (MHC) are polymorphic. Allelic variation of the coding region of these genes is involved in the antigen presentation and is associated with susceptibility to certain autoimmune diseases. The DR region is unique among human class II regions