Polymorphism in the regulatory region of
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Pascale Louis; Jean-FranΓ§ois Eliaou; Sophie Kerlan-Candon; ValΓ©rie Pinet; Rachel
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Article
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1993
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Springer-Verlag
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English
β 596 KB
Class II genes of the human major histocompatibility complex (MHC) are polymorphic. Allelic variation of the coding region of these genes is involved in the antigen presentation and is associated with susceptibility to certain autoimmune diseases. The DR region is unique among human class II regions