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Polymorphism in the upstream regulatory region of DQA1 genes and DRB1, QAP, DQA1, and DQB1 haplotypes in the German population

✍ Scribed by Haas, Johannes Peter; Kimura, Akinori; Andreas, Adriane; Hochberger, Martina; Keller, Elisabeth; Brünnler, Günther; de la Paz Bettinotti, Maria; Nevinny-Stickel, Claudia; Hildebrandt, Bernhard; Sierp, Gabriele; Sasazuki, Takehiko; Albert, Ekkehard

Book ID
122575860
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
785 KB
Volume
39
Category
Article
ISSN
0198-8859

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✍ Zhu Yao; Akinori Kimura; Klaus Hartung; Peter J. Haas; Andrea Volgger; Günter Br 📂 Article 📅 1993 🏛 Springer-Verlag 🌐 English ⚖ 750 KB

We have investigated the DNA polymorphism for the DQA1 promoter region (QAP) and HLAclass II DRB1, DQA1, and DQB1 genes in 178 central European patients with Systemic lupus erythematosus (SLE) using polymerase chain reaction and Dig-ddUTP labeled oligonucleotides. Increased frequencies of DRBl\*02 a