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Polymorphism in the promoter region of the NFKB1 gene increases the risk of sporadic colorectal cancer in Swedish but not in Chinese populations

✍ Scribed by Lewander, Andreas; Butchi, Anil Kumar Reddy; Gao, Jingfang; He, Lu-Jun; Lindblom, Annika; Arbman, Gunnar; Carstensen, John; Zhang, Zhi-Yong; The Swedish Low-Risk Colorectal Can, ; Sun, Xiao-Feng

Book ID
120535303
Publisher
Informa plc
Year
2007
Tongue
English
Weight
109 KB
Volume
42
Category
Article
ISSN
0036-5521

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## Abstract __MKK4__ (mitogen‐activated protein kinase kinase 4, NM\_003010.2), which belongs to the mitogen‐activated protein kinase pathways, possesses functions in tumorigenesis. We hypothesized the genetic variants in __MKK4__ gene may alter its functions and thus cancer risk. In current hospit