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Polymorphism in microRNA-196a2 contributes to the risk of cardiovascular disease in type 2 diabetes patients

✍ Scribed by Buraczynska, Monika; Zukowski, Pawel; Wacinski, Piotr; Ksiazek, Katarzyna; Zaluska, Wojciech

Book ID
124136742
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
179 KB
Volume
28
Category
Article
ISSN
1056-8727

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Hox gene clusters play an important role during cardiac septation to valve formation in different species, and the miR-196a-HOXB8-Sonic hedgehog signaling pathway is of particular interest. Recently, we found that a genetic variant of rs11614913 in the miR-196a2 sequence could alter mature miR-196a