Extensive gene conversion at the PMS2 DN
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Bruce E. Hayward; Michel De Vos; Elizabeth M.A. Valleley; Ruth S. Charlton; Grah
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Article
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2007
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John Wiley and Sons
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English
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## Communicated by David Cooper Mutations of the PMS2 DNA repair gene predispose to a characteristic range of malignancies, with either childhood onset (when both alleles are mutated) or a partially penetrant adult onset (if heterozygous). These mutations have been difficult to detect, due to inte