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Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases

✍ Scribed by P.I. Mackenzie; P.A. Gregory; R.H. Lewinsky; S.N. Yasmin; T. Height; R.A. McKinnon; D.A. Gardner-Stephen


Book ID
113923564
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
236 KB
Volume
207
Category
Article
ISSN
0041-008X

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Variation of hepatic glucuronidation: No
✍ Ursula Ehmer; Arndt Vogel; Jan Karl SchΓΌtte; Britta Krone; Michael P. Manns; Chr πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 138 KB

UDP-glucuronosyltransferases are a family of drug metabolizing enzymes contributing to hepatic drug metabolism and protection against environmental toxins. The aim of this study was to identify polymorphisms at the human UGT1A gene locus and to characterize their function and potential association w