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Polymorphic human gene(s) determines differential susceptibility of CD4 lymphocytes to infection by certain HIV-1 isolates

โœ Scribed by Lisa M. Williams; Miles W. Cloyd


Book ID
113209441
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
715 KB
Volume
184
Category
Article
ISSN
0042-6822

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## Abstract Within the brain, HIVโ€1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in contrast to microglia. We aimed to determine whether chemokine receptors play a role in mediating CD4โ€independent HIVโ€1 entry into astr