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Polymers as Biomaterials

✍ Scribed by Christian Braud, Michel Vert (auth.), Shalaby W. Shalaby, Allan S. Hoffman, Buddy D. Ratner, Thomas A. Horbett (eds.)


Publisher
Springer US
Year
1985
Tongue
English
Leaves
383
Edition
1
Category
Library

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✦ Synopsis


Nearly 4000 years ago, the Egyptians used linen, a natural polymeric material, for suturing wounds. About 600 B.C., the Indians used other forms of natural polymers such as cotton, horse hair, and leather in repairing wounds. Wound closure procedures using silk sutures, based mostly on polypeptides, are likely to have been practiced during the second century. Surgical application of natural polymers continued to represent the major use of polymers until the twentieth century. Not too long after the development of several major synthetic polymers, their use in biomedical applications has attracted the attention of many reΒ­ searchers and clinicians. Over the past few years, interest in the biomedical applications of polymers has grown considerably. This has been the result of the inevitable collaborative efforts of inΒ­ novative materials scientists, engineers and clinicians. The esΒ­ tablishment of the Society for Biomaterials, in our opinion, cataΒ­ lyzed the growing interest in the use of polymers for biomedical application. In a major effort to bring team players even closer, a five-day symposium on "Polymers as Biomaterials" was held in Seattle, WashingΒ­ ton, in March, 1983 as part of the national meeting of the American Chemical Society. The symposium was designed to provide a forum for communicating technical and clinical data to colleagues with a broad spectrum of interest in the biomedical applications of polymers.

✦ Table of Contents


Front Matter....Pages i-x
Poly(Ξ²-Malic Acid) as a Source of Polyvalent Drug Carriers: Possible Effects of Hydrophobic Substituents in Aqueous Media....Pages 1-15
Polypentapeptide of Elastin as an Elastomeric Biomaterial....Pages 17-32
Development of Non-Thrombogenic Materials....Pages 33-38
The Use of Polyacrylates in the Microencapsulation of Mammalian Cells....Pages 39-50
Melt Spinning of Poly-L-Lactide and Hydrolysis of the Fiber in Vitro....Pages 51-65
Some Morphological Investigations on an Absorbable Copolyester Biomaterial Based on Glycolic and Lactic Acid....Pages 67-92
Structural Identification of CIS -Platinum II Polyhydrazines....Pages 93-109
Fluorescence in Polymers: 2-Diphenylacetyl-1, 3-Indanedione-1-Imine Derivatives in Polymer Matrices....Pages 111-120
An XPS and SEM Study of Polyurethane Surfaces: Experimental Considerations....Pages 121-133
Polymer Surfaces Possessing Minimal Interaction with Blood Components....Pages 135-147
Thermodynamic Assessment of Platelet Adhesion to Polyacrylamide Gels....Pages 149-165
Reproducible Response of Certain Polymers to Changes in the Surrounding Environment....Pages 167-179
Mechanism of the Biodegradation of Polycaprolactone....Pages 181-192
Swelling Behavior of Glucose Sensitive Membranes....Pages 193-207
Selected Aspects of Cell and Molecular Biology of In Vivo Biocompatibility....Pages 209-223
Molecular Design of Materials Having an Ability to Differentiate Lymphocyte Subpopulations....Pages 225-239
Attachment of Staphylococci to Various Synthetic Polymers....Pages 241-255
Blood Compatibility of Polyethylene and Oxidized Polyethylene in a Canine A-V Series Shunt:Relationship to Surface Properties....Pages 257-277
Polymer Based Drug Delivery:Magnetically Modulated and Bioerodible Systems....Pages 279-292
Oral Sustained Release Drug Delivery System Using Polymer Film Composites....Pages 293-303
Chemical Characterization of an Immobilized Heparin:Heparin-PVA....Pages 305-315
Tumorcidal Activation and Kinetics of Ectoenzyme Production Elicited by Synthetic Polyanions....Pages 317-322
A Responsive Hydrogel as a Means of Preventing Calcification in Urological Prostheses....Pages 323-332
Potassium Ion Transport through Hydrogel Membranes in the Presence of Blood Components: Plasma Proteins....Pages 333-346
Influence of Gel and Solute Structure on In Vitro and In Vivo Release Kinetics From Hydrogels....Pages 347-360
Interaction Between Blood Components and Hydrogels With Poly(Oxyethylene) Chains....Pages 361-374
Use of Methyl Cyanoacrylate (MCA) as a Sclerosing Agent in Female Sterilization: Effect of Inhibitors and Radioopaque Additives on MCA Polymerization In Vitro and on Oviduct Occlusion In Vivo in Rabbits....Pages 375-385
Back Matter....Pages 387-389

✦ Subjects


Polymer Sciences


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