Polymerizable dendrimers. Synthesis of a symmetrically branched methacryl derivative bearing eight ester groups

✍ Scribed by Georg Draheim; Helmut Ritter

• Publisher: John Wiley and Sons
• Year: 1995
• Tongue: English
• Weight: 892 KB
• Volume: 196
• Category: Article
• ISSN: 1022-1352
• DOI: 10.1002/macp.1995.021960711

✦ Synopsis

Abstract

The synthesis of chiral acryl and methacryl derivatives containing four ester groups, tetramethyl 5‐((meth)acryloylamino)isophthalamido‐di‐2L‐succinate (2a and 2b), was done by condensation of 5‐(N‐acryloylamino)isophthalic acid (1a) or 5‐(N‐methacrylamino)isophthalic acid (1b) with L‐aspartic acid dimethyl ester in a mole ratio of 1:2. In a similar way, a methacryl monomer bearing eight ester groups, octamethyl 5,5′‐[5‐(methacryloylamino)‐isophthalamido]bis(isophthalamido)tetra‐2L‐succinate (6b), was obtained using the Z‐protected intermediate tetramethyl 5‐(benzyloxycarbonylamino)isophthalamido‐di‐2L‐succinate (4). The monomers were homopolymerized radically with AIBN as initiator, yielding optically active polymers and oligomers (2a′, 2b′ and 6b′) with branched side groups and degree of polymerization P~n~ between 2 and 23, depending on the architecture of the monomers.