Polymeric Systems for Controlled Drug Release

✍ Scribed by Uhrich, Kathryn E.; Cannizzaro, Scott M.; Langer, Robert S.; Shakesheff, Kevin M.

• Book ID: 115459466
• Publisher: American Chemical Society
• Year: 1999
• Tongue: English
• Weight: 356 KB
• Volume: 99
• Category: Article
• ISSN: 0009-2665
• DOI: 10.1021/cr940351u

✦ Synopsis

Contents

I. Introduction 3181 A. Need for Controlled Release Systems 3181 B. Methods of Controlled Release 3181 C. Scope of Polymer Systems 3183 II. Mechanisms of Controlled Drug Release Using Polymers 3183 A. Temporal Controlled 3183 B. Distribution Controlled 3189 III. Polymers Used for Controlled Drug Release 3189 A. Overview 3189 B. Poly(esters) 3190 1. Poly(lactic acid), Poly(glycolic acid), and Their Copolymers 3191 2. Poly(ethylene glycol) Block Copolymers 3191 C. Poly(ortho esters) 3192 D. Poly(anhydrides) 3193 1. Poly(anhydride-imides) 3194 2. Poly(anhydride-esters) 3194 E. Poly(amides) 3194 1. Poly(iminocarbonates) 3195 F. Phosphorus-Containing Polymers 3196 1. Poly(phosphazenes) 3196 2. Poly(phosphoesters) 3196 IV. Conclusions 3196 V. Acknowledgments 3197 VI. References 3197