𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Polymeric micelles anchored with TAT for delivery of antibiotics across the blood–brain barrier

✍ Scribed by Lihong Liu; Subbu S. Venkatraman; Yi-Yan Yang; Kun Guo; Jia Lu; Beiping He; Shabbir Moochhala; Lijing Kan


Publisher
Wiley (John Wiley & Sons)
Year
2008
Tongue
English
Weight
273 KB
Volume
90
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Genetic engineering of a lysosomal enzym
✍ Ruben J. Boado; Yun Zhang; Yufeng Zhang; Chun-fang Xia; Yuntao Wang; William M. 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 2 views

## Abstract Mucopolysaccharidosis Type I, Hurler's Syndrome, is a lysosomal storage disorder that affects the brain. The missing enzyme, α‐L‐iduronidase (IDUA), does not cross the blood‐brain barrier (BBB). To enable BBB transport of the enzyme, human IDUA was fused to the carboxyl terminus of the

Genetic engineering, expression, and act
✍ Ruben J. Boado; Yufeng Zhang; Yun Zhang; William M. Pardridge 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 307 KB 👁 1 views

## Abstract Neurotrophins, such as brain derived neurotrophic factor (BDNF), do not cross the blood–brain barrier (BBB). Certain monoclonal antibodies (MAb) to the human insulin receptor (HIR) do cross the BBB via receptor‐mediated transport, and can act as a molecular Trojan horse to ferry across