Polymer-supported reagents : a simple and efficient method for the synthesis of esters of 2,4-dichlorophenoxyacetic acid

✍ Scribed by M.M. Salunkhe; M.T. Thorat; R.B. Mane; P.P. Wadgaonkar

• Publisher: Elsevier Science
• Year: 1989
• Tongue: English
• Weight: 141 KB
• Volume: 25
• Category: Article
• ISSN: 0014-3057
• DOI: 10.1016/0014-3057(89)90144-4

✦ Synopsis

Insoluble polymer-supported nucleophilic reagent was prepared by treatment of the sodium salt of 2,4-dichlorophenoxyacetic acid with Amberlite IRA-400 (CI-form). This reagent was treated with appropriate halogen compounds in ethanol at room temperature to give the corresponding esters of 2,4-dichlorophenoxyacetic acid in high yields. The advantages of this method are the mild reaction conditions and the ease of isolation of products.