The reaction of functional&d mono or dichlorinated materials la-6a with an excess of lithium and a catalytic amount of a napbthalene supported polymer (P-152, easily prepared by radical copolymerisation of 2\_vinylnaphthalene, styrene and divinylbenzene) in THF either in the presence (Barbier-type c
Polymer supported naphthalene-catalysed lithiation reactions
✍ Scribed by Cecilia Gómez; Sonia Ruiz; Miguel Yus
- Book ID
- 104258641
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 309 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The reaction of functionalised mono or dichlorinated materials la-6a with an excess of lithium and a catalytic amount of a naphthalene (PN) or biphenyl (PB) supported polymer (eassily prepared by radical copolymerisation of 2-vinylnaphthalene or 4-vinylbiphenyl with vinylbenzene and divinylbenzene)
Polymer Supported Naphthalene-Catalyzed Lithiation Reactions. -Lithiation of functionalized organic chlorides (I) is effectively promoted by a naphthalene supported polymer. Quenching with electrophiles (II) leads to the expected products (III). Dichlorides (IV) and (VII) undergo an analogous react
AbstractÐNaphthalene catalysed reductive lithiation of various chloroazines (1, 7,10,13) in the presence of different electrophiles yields, after hydrolysis, the expected functionalised heterocycles with one (2, 8), two (11, 14a±d) and three nitrogen atoms in the ring (14e,f). This methodology allow