Parallel synthesis of dihydropyrimidinon
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Alessandro Dondoni; Alessandro Massi
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Article
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2001
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Elsevier Science
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French
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An efficient synthesis of an array of 3,4-dihydropyrimidin-2-(1H)-ones using solid-supported ytterbium(III) reagent from aldehydes, 1,3-dicarbonyl compounds and urea (Biginelli reaction) under solvent-free conditions is described. Purification of each member of the library was carried out using a co