Asymmetric synthesis of α-substituted am
✍
Kolb, Michael ;Barth, Jacqueline
📂
Article
📅
1983
🏛
John Wiley and Sons
🌐
English
⚖ 1015 KB
## Abstract The asymmetric synthesis of α‐substituted α‐amino acids and propargylamines is described. As chiral auxiliary we used (__S__)‐(–)‐1‐dimethoxymethyl‐2‐methoxymethylpyrrolidine (SDMP, **1**). Treatment of the amino acids or amines with SDMP **1** afforded the corresponding amidines **C**,