𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Polymer-Peptide Block Copolymers – An Overview and Assessment of Synthesis Methods

✍ Scribed by Hana Robson Marsden; Alexander Kros

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
801 KB
Volume
9
Category
Article
ISSN
1616-5187

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Incorporating peptide blocks into block copolymers opens up new realms of bioactive or smart materials. Because there are such a variety of peptides, polymers, and hybrid architectures that can be imagined, there are many different routes available for the synthesis of these chimera molecules. This review summarizes the contemporary strategies in combining synthesis techniques to create well‐defined peptide‐polymer hybrids that retain the vital aspects of each disparate block. Living polymerization can be united with the molecular‐level control afforded by peptide blocks to yield block copolymers that not only have precisely defined primary structures, but that also interact with other (bio)molecules in a well defined manner.

magnified image

📜 SIMILAR VOLUMES

Synthesis and ordered structure of amphi
Synthesis and ordered structure of amphipatic block copolymers with a saccharide and a peptide block
✍ André Douy; Bernard Gallot 📂 Article 📅 1980 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 671 KB

## Abstract Amphipatic block copolymers (OβEb) with a hydrophilic saccharide block and a hydrophobic polypeptide block were synthesized. In these copolymers the saccharide block is the glyco‐amino acid Oβ from ovomucoid and the peptide block (Eb) is a poly(γ‐benzyl‐L‐glutamate) block. Copolymers Oβ

Synthesis of ABC-Triblock Peptide-Polyme
Synthesis of ABC-Triblock Peptide-Polymer Conjugates for the Positioning of Peptide Segments within Block Copolymer Aggregates
✍ Mattijs G. J. ten Cate; Hans G. Börner 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB

## Abstract The synthesis of amphiphilic ABC‐triblock peptide‐polymer conjugates comprising a central oligopeptide segment and terminal hydrophilic poly(ethylene oxide) (PEO) as well as hydrophobic poly(butyl acrylate) (PBA) blocks is described. In aqueous solution, the amphiphilic segments of thes

Assessing the Intake of Contaminants and
Assessing the Intake of Contaminants and Nutrients: An Overview of Methods
✍ Barbara J. Petersen; Leila M. Barraj 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 86 KB

The methods being applied to assess the intake of food contaminants or nutrients from one or more foods are reviewed and their advantages and disadvantages are discussed. Methods currently being used for estimating the joint intake of food contaminants or nutrients from several foods depend on the d

New block copolymers—III. Synthesis, cha
New block copolymers—III. Synthesis, characterization and crosslinking studies of an (A-B)n type block copolymer
✍ B.M. Mahato; S.C. Shit; S. Maiti 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 421 KB

A new block copolymer was prepared by low temperature polycondensation between (acid chloride)-terminated poly(trimethylene terephthalate), as the hard block, and amine-terminated butadiene/acrylonitrile rubber, as the soft block. The polymer was characterized by elemental (nitrogen) analysis, i.r.

An Improved Rapid Synthesis of Oligo(p-b
An Improved Rapid Synthesis of Oligo(p-benzamide) Block Copolymers
✍ Hannah M. König; Andreas F. M. Kilbinger 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 454 KB

## Abstract We describe a new synthesis that allows the preparation of oligo(__p__‐benzamide)s up to the heptamer on solid support without the need of semi‐temporary amide __N__‐protective groups. With increase in length, the solubility of oligo(__p__‐benzamide)s reduces dramatically. Even the tetr