Flocculation by a cationic polymer of sulfamerazine suspensions containing a wetting agent was evaluated. Suspensions with sufficient surfactant concentrations to ensure complete wetting were deflocculated. When the anionic surfactant, dioctyl sodium sulfosuccinate, was used as a wetting agent, the
Polymer-induced flocculation of pharmaceutical suspensions
β Scribed by Alvin Felmeister; Gale M. Kuchtyak; Susan Koziol; Charles J. Felmeister
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 165 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
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A polymer coil with weak affinity for the solid surface makes a flexible bridge between particles by reversible adsorption. When the coil size is comparable to particle diameter in solution, the suspensions flocculated by reversible bridging show shear-thickening flow in a narrow range of shear rate