Polymer-Based Sustained-Release Dosage Forms for Protein Drugs, Challenges, and Recent Advances

PLGA based drug delivery systems (DDS) f

PLGA based drug delivery systems (DDS) for the sustained release of insulin: insight into the protein/polyester interactions and the insulin release behavior

✍ Verónica Lassalle; María Luján Ferreira 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 281 KB 👁 1 views

## Abstract **BACKGROUND:** Drug delivery systems (DDS) were designed using insulin as model drug and poly (lactic–co‐glycolic) copolymers (PLGA) as polymeric matrix. The carriers were synthesized by direct self‐assembly of the insulin and the polyester under mild conditions. **RESULTS:** The kind