Polyketides from a marine sponge-derived fungus Mycelia sterilia and proton–proton long-range coupling
✍ Scribed by Gao Hao; Zhang Qing-Hua; Jiang Miao-Miao; Tang Jin-Shan; Miao Cheng-Du; Hong Kui; Namikoshi Michio; Wang Nai-Li; Yao Xin-Sheng
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 190 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.2338
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✦ Synopsis
Abstract
A series of polyketide‐originated metabolites (1–5) were isolated from a marine sponge‐derived fungus Mycelia sterilia. Of these, 1–3 were new compounds. Their structures were elucidated by spectroscopic methods as (4__R__*, 5__S__*, 6__S__*, 8__S__*, 13__R__*)‐1‐(2,8‐dihydroxy‐1,2,6‐trimethyl‐1,2,6,7,8,8a‐hexahydro‐naphthalen‐1‐yl)‐3‐methoxy‐propan‐1‐one (1), 4,8‐dihydroxy‐7‐(2‐hydroxy‐ethyl)‐6‐methoxy‐3,4‐dihydro‐2__H__‐naphthalen‐1‐one (2) and 1‐methyl‐naphthalene‐2,6‐dicarboxylic acid (3). In 1, the proton–proton long‐range coupling phenomenon claimed attention and was discussed. Copyright © 2008 John Wiley & Sons, Ltd.