Polyinosinic Acid Blocks Adeno-Associated Virus Macrophage Endocytosis In Vitro and Enhances Adeno-Associated Virus Liver-Directed Gene Therapy In Vivo
β Scribed by van Dijk, Remco; Montenegro-Miranda, Paula S.; Riviere, Christel; Schilderink, Ronald; ten Bloemendaal, Lysbeth; van Gorp, Jacqueline; Duijst, Suzanne; de Waart, Dirk R.; Beuers, Ulrich; Haisma, Hidde J.; Bosma, Piter J.
- Book ID
- 121298113
- Publisher
- Mary Ann Liebert
- Year
- 2013
- Tongue
- English
- Weight
- 286 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1043-0342
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Increased efficiency of transgene expression is desired for virusβmediated gene delivery. In the present study, we examined the effect of calcium phosphate (CaPi) on recombinant adenoβassociated virus (rAAV)βmediated insulin therapy in diabetic animals. ## Methods The r
## Abstract ## Background Successful liver gene therapy depends on efficient gene transfer techniques and longβlasting gene expression after successful transfer. Over the last decades, important progress has been made with the introduction of viral vectors using animal models, although their use i