Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
✍ Scribed by Ruderfer, D M; Fanous, A H; Ripke, S; McQuillin, A; Amdur, R L; Gejman, P V; O'Donovan, M C; Andreassen, O A; Djurovic, S; Hultman, C M; Kelsoe, J R; Jamain, S; Landén, M; Leboyer, M; Nimgaonkar, V; Nurnberger, J; Smoller, J W; Craddock, N; Corvin, A; Sullivan, P F; Holmans, P; Sklar, P; Kendler, K S
- Book ID
- 126727141
- Publisher
- Nature Publishing Group
- Year
- 2013
- Tongue
- English
- Weight
- 849 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1359-4184
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Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80% 1,2 . We performed a genome-wide association study of 3,322 European individuals with schizophrenia and 3,587 contro