To characterize acute-phase hepatitis B virus (HBV)-specific T cell responses associated with self-limited and persistent HBV infections, we compared a patient with acute HBV/HCV coinfection, who was able to control HCV but developed chronic hepatitis B, with patients who resolved acute HBV infectio
Polyfunctional HCV-specific T-cell responses are associated with effective control of HCV replication
✍ Scribed by Donatella Ciuffreda; Denis Comte; Matthias Cavassini; Emiliano Giostra; Leo Bühler; Monika Perruchoud; Markus H. Heim; Manuel Battegay; Daniel Genné; Beat Mulhaupt; Raffaele Malinverni; Carl Oneta; Enos Bernasconi; Martine Monnat; Andreas Cerny; Christian Chuard; Jan Borovicka; Gilles Mentha; Manuel Pascual; Jean-Jacques Gonvers; Giuseppe Pantaleo; Valérie Dutoit
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 630 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Hepatitis C virus (HCV) RNA persistence in the liver has been described even after apparent resolution of HCV infection. Because T‐cell reactivity plays a role in recovery from HCV infection, virus‐specific T‐cell responses were investigated in apparently recovered individuals in whom h
Virus-specific CD8+ T cells play a major role in antiviral immune defenses; their significance in the transplant setting, however, is unclear. In the present study, we asked whether hepatitis C virus (HCV)-specific CD8+ T cells were detectable in the presence of an immunosuppressive treatment and wh