Synthesis of 1-(m-Hydroxybenzyl)-Substit
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Els Mannekens; Marco Crisma; Sylvia Van Cauwenberghe; Dirk Tourwé
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Article
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2003
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John Wiley and Sons
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English
⚖ 175 KB
## Abstract __N__‐Glycyl‐(1__R__,3__S__)‐1‐(__m__‐hydroxybenzyl)‐1,2,3,4‐tetrahydroisoquinoline‐3‐carboxylic acid (Tic) was prepared as a Tyr‐Tic dipeptide mimetic for exploration of its potential as a delta opioid receptor selective ligand. The compound was successfully obtained by a stereoselecti