Poly(ethylene terephthalate)/hydroxyapatite biomaterials: Preparation, characterization, and in vitro bioactivity

✍ Scribed by Punnama Siriphannon; Pathavuth Monvisade

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 251 KB
• Volume: 88A
• Category: Article
• ISSN: 1549-3296
• DOI: 10.1002/jbm.a.31797

✦ Synopsis

Abstract

Poly(ethylene terephthalate)/hydroxyapatite (PET/HAp) composites were prepared by mixing HAp powder with a mixture solution of cyclic oligo(ethylene terephthalate) (C‐OET) and dibutyl tinoxide catalyst in dichrolomethane, and then shaping the precomposites in cylindrical pellets. The C‐OET in the precomposites was ring‐opening polymerized (ROP) to PET under vacuum at 250°C for 24 h. The PET/HAp composites were formulated with HAp to PET ratios of 60:40 (H6P4) and 50:50 (H5P5). The ROP‐PET in the composites was present as a thin‐layer coating on the HAp grains and evenly distributed throughout the samples. Compressive strength of the PET/HAp composites was significantly increased from 8 MPa of the H10P0 to 17 and 29 MPa for H6P4 and H5P5, respectively. In vitro bioactivity of the PET/HAp composites was studied by soaking in simulated body fluid (SBF) at 36.5°C for 7–28 days. After prolonged soaking, the HAp nanocrystals precipitated from the SBF solution and formed as a layer of globular aggregates, coated on the composite surfaces. The H6P4 composite showed faster formation rate of nano‐HAp than the H5P5 composite, indicating that the bioactivity of PET/HAp composites depended on the amount of HAp. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res 2009