Polyethylene glycol effect on the oxygenated and hypoxic isolated perfused rat kidney
β Scribed by Kopolyovic, J. ;Brezis, M. ;Spokes, K. ;Rosen, S.
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 1012 KB
- Volume
- 414
- Category
- Article
- ISSN
- 0174-7398
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## Abstract The objective of this study was to determine the effects of repetitive ischemia on myocardial oxygen tension (pO~2~), consumption, and delivery in crystalloid normoperfused (perfuβsion pressure > 70 mmHg) and hypoperfused (perfusion pressure Λ50 mmHg) constant flow isolated rat hearts.
In the rat pulmonary vasculature perfused with blood in situ vasoconstriction induced by hypoxia was reversed by isoprenaline (doses greater than 1 ng) and adrenaline (doses greater than 30 ng) and exacerbated by phenylephrine but not UK 14304. Doses of adrenaline less than 30 ng had no effect, exce
Abbreviations: IPRL, isolated perfused rat liver preparation; P 0 , zero-flow intercept of the regression line calculated from pressure-flow data relating to the flow rates above 20 mL/min; G max , maximum portal vascular conductance or the reciprocal gradient of the regression line above; H A , hep