✦ LIBER ✦

Poly(ethylene glycol) as solvent and polymer support in the microwave assisted parallel synthesis of aminoacid derivatives

✍ Scribed by Bérengère Sauvagnat; Frédéric Lamaty; René Lazaro; Jean Martinez

Book ID: 104210679
Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 148 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)01067-4

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✦ Synopsis

A Schi base protected glycine supported on a soluble polymer such as poly(ethylene glycol) reacted readily with various electrophiles in the presence of an inorganic base under microwave activation. It was shown in this study that the polymer support also serves as solvent in these reactions. Various a-aminoacids derivatives could be synthesized using this method.

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