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Poly(d,l-lactide-ran-ε-caprolactone)-poly(ethylene glycol)-poly(d,l-lactide-ran-ε-caprolactone) as parenteral drug-delivery systems

✍ Scribed by Hanjin Cho; Dongjun Chung; An Jeongho

Book ID: 108069239
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 670 KB
Volume: 25
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2003.09.106

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## SYNOPSIS Blends of poly(L-lactide) (PLLA) and poly(e-caprolactone) (PCL) were prepared in a corotating twin screw miniextruder (40 rpm, 200"). It was attempted to prepare multiblock copolymers by allowing a controlled number of transesterification reactions. Various catalysts (n-Bu,SnOMe, Sn(Oc