Poly[d(A-T)-Cs+] conformations studied by IR spectroscopy

✍ Scribed by S. Adam; P. Bourtayre; J. Liquier; J. A. Taboury; E. Taillandier

• Book ID: 101718885
• Publisher: Wiley (John Wiley & Sons)
• Year: 1987
• Tongue: English
• Weight: 490 KB
• Volume: 26
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.360260207

✦ Synopsis

Infrared absorption and ir linear dichroism measurements have been performed on poly[d(A-T)-

Cs'] f i l m s at various relative humidities. At high relative humidity, samples are in a B form; at low relative humidity, in a C form. The B + C conformational transition is shown to be a noncooperative one corresponding to a gradual evolution of the backbone geometry of the polynucleotide within the B family. The C-form-type spectrum is characteristic of an alternated phosphodiester chain with a dinucleotidic repeat unit.