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Polycyclic N-Heterocyclic Compounds, Part 71: Synthesis and Bronchodilator Evaluation of 5-Substituted 1,2-Dihydrofuro[3,2-f][1,7]naphthyridines and Related Compounds

✍ Scribed by Kensuke Okuda; Tetsuo Matsushita; Takashi Hirota; Kenji Sasaki

Book ID: 115558818
Publisher: Journal of Heterocyclic Chemistry
Year: 2012
Tongue: English
Weight: 181 KB
Volume: 49
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.846

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## Abstract Some novel 5‐hydroxyalkylamino‐1,2‐dihydrothieno[2,3‐__h__][1,6]naphthyridines were prepared by the reaction of 5‐chloro‐1,2‐dihydrothieno[2,3‐__h__][1,6]naphthyridine derivatives with some aminoalcohols in the presence of base. These derivatives were cyclized to the corresponding imida