Cytochrome P450IID6-specific CD8 T cell
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Maria Serena Longhi; Munther J. Hussain; Dimitrios P. Bogdanos; Alberto Quaglia;
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Article
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2007
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John Wiley and Sons
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English
⚖ 697 KB
Autoimmune hepatitis type 2 (AIH-2) is a severe organ-specific disorder characterized by liver kidney microsomal antibody type 1 targeting cytochrome P4502D6 (CYP2D6). Growing evidence implicates the involvement of CD8 T cell immune responses in its pathogenesis. We investigated CYP2D6-specific CD8