Polychlorinated ketones. II. Dechlorination of highly chlorinated ketones with trivalent phosphorus compounds

The reaction of pentasubstituted 3-hydro

The reaction of pentasubstituted 3-hydroxy-1,2-dioxolanes (hemiperketals) with trivalent phosphorus compounds: Synthesis of β-hydroxy ketones

✍ Alfons L. Baumstark; Pedro C. Vasquez; Yaxiong Chen 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB

The reaction of a series of 4,4-dimethyl-3,5,5-(R3, R2, ## RI)-3-hydroxy-I,2-dioxolanes la-d [la (R, with trimethyl phosphite or triphenylphosphine produced the p-hydro.xy ketones, 2a-d [(R,R#70H)CMe2-COR3], and the corresponding phosphoryl compounds in high yield. The reactions were slow (-24 ho