Polycation-based nanoparticle delivery for improved RNA interference therapeutics
✍ Scribed by Howard, Kenneth A; Kjems, Jørgen
- Book ID
- 120898337
- Publisher
- Informa plc
- Year
- 2007
- Tongue
- English
- Weight
- 696 KB
- Volume
- 7
- Category
- Article
- ISSN
- 5847-4714
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Therapeutics based on small interfering RNA (siRNA) have a huge potential for the treatment of disease but requires sophisticated delivery systems for in vivo applications. Lipid nanoparticles (LNP) are proven delivery systems for conventional small molecule drugs with over eight approved LNP drugs.
Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular prope