✦ LIBER ✦

Polybrominated biphenyl induction of cytochrome P450 mixed function oxidase activity in primary rat and human hepatocytes

✍ Scribed by Jill C. Merrill; Dale J. Beck; Don A. Kaminski; A.P. Li

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 561 KB
Volume: 99
Category: Article
ISSN: 0300-483X
DOI: 10.1016/0300-483x(95)03009-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Influence of single and concurrent clofi

Influence of single and concurrent clofibrate and phenobarbital administration on cytochrome P450-dependent mixed function oxidase activities and peroxisome proliferation in male rat liver

✍ Close, Ian ;Shackleton, Gareth ;Goldfarb, Peter S. ;Gibson, G. Gordon ;Sharma, R 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 599 KB

The influence of both single and concurrent administration of phenobarbital and clofibrate on hepatomegaly, cytochrome P450-dependent mixed function oxidase activities, and peroxisome proliferation in male rat liver have been studied. Both xenobiotics separately increase the liver: body weight ratio

Differential localization of microsomal

Differential localization of microsomal mixed function oxidase activity in periportal and perivenous hepatocytes isolated from rat liver

✍ Yamazaki Hiromi; Nishiguchi Keiko; Serasinghe Palitha; Nakanishi Suehiro 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 374 KB

The metabolism of leukotrienes, detoxifi

The metabolism of leukotrienes, detoxification of reactive oxygen species and the activity of the cytochrome P450 mixed function oxidase system in sensitised guinea-pig lungs

✍ M.H. Grant; I.W. Rodger 📂 Article 📅 1991 🏛 Elsevier 🌐 English ⚖ 434 KB

In sensitised guinea-pig lungs alterations in leukotriene (LT) metabolism occurred which resulted in an increase in LTD4 synthesis and a reduction in its catabolism. This may lead to an increase in the concentration of this potent spasmogen in the sensitised lungs. The LTs may cause hyperreactivity

Evaluation of cell viability, mixed func

Evaluation of cell viability, mixed function oxidase activity, metallothionein induction, and genotoxicity in rainbow trout hepatocytes exposed to industrial effluents: II. Validation of the rainbow trout hepatocyte model for ecotoxicity testing of industrial wastewater

✍ Gagn�, F. ;Blaise, C. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 100 KB 👁 2 views

Primary cultures of rainbow trout hepatocyte are proposed as an alternative to the rainbow trout bioassay for evaluating mortality, hepatic metallothionein and cytochrome P4501A activity inductions, and hepatic DNA damage with industrial effluents. The validation study sought to assess the ( ) perfo