## Abstract Biodegradable poly(aspartic acid) (PASP) hydrogel and PASP/gelatin complex were prepared to evaluate their potential application as pHโsensitive matrices for controlled protein release. Entrapment of myoglobin (Mb) and its release were compared between the two types of carriers. It was
โฆ LIBER โฆ
Polyanion/gelatin complexes as pH-sensitive gels for controlled protein release
โ Scribed by H. L. Jiang; K. J. Zhu
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 188 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0021-8995
- DOI
- 10.1002/app.1231
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## Abstract **Summary:** An ampholytic __N__โcarboxyethyl chitosan (CEC), with various isoelectric points (IPs), was synthesized by grafting acrylic acid on chitosan utilizing Michael's reaction. Compared to native chitosan, CEC has enhanced water solubility and dramatically accelerated enzymatic d