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Polyamine-Substituted Gadolinium Chelates: A New Class of Intracellular Contrast Agents for Magnetic Resonance Imaging of Tumors

✍ Scribed by Wolf, Markus; Hull, William E.; Mier, Walter; Heiland, Sabine; Bauder-Wüst, Ulrike; Kinscherf, Ralf; Haberkorn, Uwe; Eisenhut, Michael


Book ID
127266342
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
219 KB
Volume
50
Category
Article
ISSN
0022-2623

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## Abstract We have developed a new class of magnetic resonance imaging contrast agents with large proton relaxation enhancements and high molecular relaxivities. The reagents are built from the polyamidoamine form of Starburs™ dendrimers in which free amines have been conjugated to the chelator 2‐