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Polyamine analogs with antitumor activity

✍ Scribed by Edwards, Michael L.; Prakash, N. J.; Stemerick, D. M.; Sunkara, S. P.; Bitonti, A. J.; Davis, G. F.; Dumont, J. A.; Bey, P.

Book ID
118054361
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
953 KB
Volume
33
Category
Article
ISSN
0022-2623

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## Background: Recent studies indicate that n-terminally bis-ethylated-polyamine analogs have significant antitumor activity in several human solid-tumor models. in this study, the in vitro and in vivo antitumor potential of the polyamine analog n(1), n(11)-diethylnorspermine (denspm) in human pros