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Poly(ADP-ribose) Glycohydrolase Is Present and Active in Mammalian Cells as a 110-kDa Protein

✍ Scribed by Eric Winstall; El Bachir Affar; Rashmi Shah; Sylvie Bourassa; A.Ivana Scovassi; Guy G. Poirier

No coin nor oath required. For personal study only.

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Direct Quantitation of Poly(ADP-Ribose)

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Scheme 1. A) Opposing roles of PARP-1 in necrotic and apoptotic death. B) Chemical quantitation of NAD + .

The specific, submicromolar-Km ADP-ribos

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