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Poly (C) avid ribonuclease estimation in patients with solid tumors: A critical evaluation

โœ Scribed by Mario Francesconi; Siegfried Meryn; Alfred M. Rogan; Stefan Szalay; Wolfgang Graninger; Christian P. Schmidbauer


Book ID
101328538
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
322 KB
Volume
53
Category
Article
ISSN
0008-543X

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Evaluation of weekly escalating doses of
โœ William J. Tester; Ross C. Donehower; Joyce L. Eddy; Charles E. Myers; Daniel C. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 525 KB

Twenty-one patients with solid tumors were treated with weekly 6-h intravenous infusions of dichloromethotrexate (DCM), with escalating doses every other week. Frequently observed toxicities included leukopenia, thrombocytopenia, and mucositis. Nausea, vomiting, diarrhea, and elevation of hepatic en