Policing styles: Notes on an empirical synthesis of Wilson and Muir

The Synthesis of [4-Carboranylalanine, 5

The Synthesis of [4-Carboranylalanine, 5-Leucine]-Enkephalin (Including an Improved Preparation of t-Butoxycarbonyl-L-o-carboranylalnine, New Derivatives of L-Propargylglycine, and a Note on Melanotropic and Opiate Receptor Binding Characteristics)

✍ Jean-Luc Fauchère; Othmar Leukart; Alex Eberle; Robert Schwyzer 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 German ⚖ 646 KB

## Abstract The title compound, an analogue of [Leu^5^]‐enkephalin with L‐__o__‐carboranylalanine replacing L‐phenylalanine in position 4, was prepared by fragment condensation. The analogue has a 3‐fold higher affinity for rat brain opiate receptors in the [^3^H]naloxone competition assay than nat