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Polarographic investigation of the Zimmermann reaction mechanism

✍ Scribed by K.G. Blass; R.J. Thibert


Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
351 KB
Volume
20
Category
Article
ISSN
0026-265X

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## Abstract The reaction mechanism of the dinuclear zinc enzyme dihydroorotase was investigated by using hybrid density functional theory. This enzyme catalyzes the reversible interconversion of dihydroorotate and carbamoyl aspartate. Two reaction mechanisms in which the important active site resid