## Abstract ## Background and Objective In developing fluorescence spectroscopy systems for the in vivo detection of preβcancer and cancer, it is often necessary to perform preliminary testing on tissue biopsies. Current standard protocols call for the tissue to be immediately frozen after biopsy
Polarized diffuse reflectance measurements on cancerous and noncancerous tissues
β Scribed by Sandeep Manhas; Mahesh K. Swami; Hari S. Patel; Abha Uppal; Nirmalya Ghosh; Pradeep K. Gupta
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 270 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1864-063X
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β¦ Synopsis
Abstract
We report the measurement of polarization parameters (linear retardance, diattenuation and depolarization) of normal and malignant tissue from human oral cavity and breast over the spectral range 390 nm to 550 nm. These parameters were determined using the 3 Γ 3 Mueller matrix, the elements of which could be determined using linear polarization measurements only. The significant differences observed in the polarization parameters of the normal and malignant tissues appear to arise because of the changes in the collagen matrix in the two tissue types. (Β© 2009 WILEYβVCH Verlag GmbH & Co. KGaA, Weinheim)
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