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Polarity of DNA entry in transformation of Streptococcus pneumoniae

✍ Scribed by Méjean, Vincent ;Claverys, Jean-Pierre

Publisher
Springer
Year
1988
Tongue
English
Weight
520 KB
Volume
213
Category
Article
ISSN
0026-8925

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Localised conversion in pneumococcal transformation is a process that spans a few nucleotides when the 5'-ATTAAT/3'-TAAGTA configuration occurs at the pairing step. It was first observed in two-point crosses between an amiA mutation (amiA36) carrying this sequence and other closely linked mutants of

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In pneumococcal transformation a particular point mutation belonging to the amiA locus is able markedly to enhance recombination frequency when crossed with any other markers of this gene. This results from a polarized conversion of the mutation towards the wild-type sequence. In this report, by sit