Heterozygous individuals carrying a "paradominant" mutation, as a rule, are phenotypically normal. Therefore, the mutation can be transmitted unperceived through many generations. The trait becomes manifest when a somatic mutation occurs during embryogenesis giving rise to loss of heterozygosity and
Poland anomaly may be explained as a paradominant trait
β Scribed by Happle, Rudolf
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 4 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0148-7299
- DOI
- 10.1002/(sici)1096-8628(19991203)87:4<364::aid-ajmg17>3.0.co;2-o
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