Pokeweed mitogen activated suppressor T-cells preferentially reduce immunoglobulin secretion by differentiated B-lymphocytes

Surface markers of cloned human T cells

Surface markers of cloned human T cells with helper or suppressor activity on pokeweed mitogen-driven B cell differentiation

✍ Maria Cristina Mingari; Giovanni Melioli; Alessandro Moretta; Giuseppe Pantaleo; 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 445 KB

## Abstract Human spleen T cells stimulated with pokeweed mitogen (PWM) were cloned under limiting conditions in microculture systems using interleukin 2 and irradiated autologous cells. Clones were screened for helper or suppressor activity on PWM‐dependent B cell differentiation by adding cell al