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Point mutations of Ha-ras and Ki-ras oncogenes in sputum specimens from lung cancer patients

✍ Scribed by He, Ling; Chen, Jia-kun; Yi, Fei; Wu, Zhong-liang; Du, Ying-xiu


Book ID
121990738
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
137 KB
Volume
14
Category
Article
ISSN
0169-5002

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K-ras mutation appears in about 60% of patients with non-small-cell lung cancer (NSCLC). This freqLency and its presence in normal appearing tissues point to the potential of ras oncogene mutation to serve as a good biomarker. Using enriched PCR (EPCR), which enables the detection of one mutant alle