## Abstract Mutated versions or overexpression of receptor tyrosine kinases such as the epidermal growth factor receptor are found frequently in various cancers. In Xiphophorus the formation of hereditary melanoma is caused by the overexpression of the __Xmrk__ oncogene locus. Xmrk is a mutationall
โฆ LIBER โฆ
Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity
โ Scribed by Yoshimura, Akihiko; Longmore, Gregory; Lodish, Harvey F.
- Book ID
- 109766756
- Publisher
- Nature Publishing Group
- Year
- 1990
- Tongue
- English
- Weight
- 539 KB
- Volume
- 348
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/348647a0
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Activating mutations in the extracellula
โ
Dirk Winnemoeller; Claudia Wellbrock; Manfred Schartl
๐
Article
๐
2005
๐
John Wiley and Sons
๐
French
โ 561 KB
A novel type of mutation in the cysteine
โ
Arlt, D H; Baur, B; Wagner, B; Hรถppner, W
๐
Article
๐
2000
๐
Nature Publishing Group
๐
English
โ 144 KB
Point mutations in the tyrosine kinase d
โ
Santoro, Massimo Mattia; Penengo, Lorenza; Minetto, Marta; Orecchia, Sara; Cilli
๐
Article
๐
1998
๐
Nature Publishing Group
๐
English
โ 564 KB
Constitutive activation of the androgen
โ
Jocelyn Cรฉraline; Marion D. Cruchant; Eva Erdmann; Philippe Erbs; Jean-Emmanuel
๐
Article
๐
2003
๐
John Wiley and Sons
๐
French
โ 278 KB
๐ 2 views
## Abstract Androgen receptor (AR) mutations that modify both the ligand binding and the transactivation capacities of the AR represent one of the mechanisms involved in the transition of prostate cancer (PCa) from androgenโdependent to androgenโindependent growth. We use a yeastโbased functional a
New point mutation (R243W) in the hormon
โ
Joachim Pohlenz; Winfried Schรถnberger; Heike Wemme; Andreas Winterpacht; Stefan
๐
Article
๐
1996
๐
John Wiley and Sons
๐
English
โ 225 KB
๐ 2 views
Histochemically demonstrable enzyme acti
โ
S. PARTANEN; K. SYRJANEN
๐
Article
๐
1982
๐
John Wiley and Sons
๐
English
โ 426 KB