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Point: Counterpoint: Hypobaric hypoxia induces/does not induce different responses from normobaric hypoxia

✍ Scribed by Millet, G. P.; Faiss, R.; Pialoux, V.


Book ID
115525079
Publisher
The American Physiological Society
Year
2012
Tongue
English
Weight
47 KB
Volume
112
Category
Article
ISSN
8750-7587

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## Abstract Tumors arise initially as avascular masses in which central hypoxia induces expression of vascular endothelial growth factor‐A (VEGF‐A) and subsequently tumor vascularization. However, VEGF‐A can also be constitutively expressed as a result of genetic events. VEGF‐A is alternatively spl